Voltage-sensitive potassium channels in Limulus ventral photoreceptors.

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Voltage-sensitive potassium channels in Limulus ventral photoreceptors

The steady-state slope conductance of Limulus ventral photoreceptors increases markedly when the membrane is depolarized from rest. The ionic basis of this rectification has been examined with a voltage-clamp technique. Tail currents that occur when membrane potential is repolarized after having been depolarized have been identified. The tail currents reverse direction at a voltage that becomes...

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A preparation of dissociated Drosophila ommatidia is described that allows single-channel and whole-cell patch-clamp analysis of currents in identified sensory neurons. Three distinct classes of voltage-sensitive potassium conductances are characterized; all were detected in distal parts of ommatidia from sevenless mutants and hence in one cell class (R1-6 photoreceptors). Rapidly inactivating ...

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Voltage-dependent conductances in Limulus ventral photoreceptors

The voltage-dependent conductances of Limulus ventral photoreceptors have been investigated using a voltage-clamp technique. Depolarization in the dark induces inward and outward currents. The inward current is reduced by removing Na+ or Ca2+ and is abolished by removing both ions. These results suggest that both Na+ and Ca2+ carry voltage-dependent inward current. Inward current is insensitive...

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Light-activated channels in limulus ventral photoreceptors.

We have investigated the light-dependent conductance of the ventral photoreceptor of Limulus by using the patchclamp technique. Our results show that ionic channels open in response to the sensory stimulus in these cells. To prepare the photoreceptors for patch-clamp recording, the glial cells and connective tissue that surround the photoreceptor were removed by teasing them away using a suctio...

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Functional significance of voltage-dependent conductances in Limulus ventral photoreceptors

The influence of voltage-dependent conductances on the receptor potential of Limulus ventral photoreceptors was investigated. During prolonged, bright illumination, the receptor potential consists of an initial transient phase followed by a smaller plateau phase. Generally, a spike appears on the rising edge of the transient phase, and often a dip occurs between the transient and plateau. Block...

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ژورنال

عنوان ژورنال: Journal of General Physiology

سال: 1978

ISSN: 0022-1295,1540-7748

DOI: 10.1085/jgp.71.1.101